A primer on viral-associated olfactory loss in the era of COVID-19.
Identifieur interne : 000A26 ( Main/Exploration ); précédent : 000A25; suivant : 000A27A primer on viral-associated olfactory loss in the era of COVID-19.
Auteurs : Zachary M. Soler [États-Unis] ; Zara M. Patel [États-Unis] ; Justin H. Turner [États-Unis] ; Eric H. Holbrook [États-Unis]Source :
- International forum of allergy & rhinology [ 2042-6984 ] ; 2020.
Abstract
Early reports have suggested that smell loss may be an early symptom associated with the pandemic known as COVID-19. The possibility that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might cause olfactory dysfunction is certainly plausible. Patients presenting to specialized smell clinics are commonly diagnosed with upper respiratory infection (URI)-associated olfactory loss and most are presumed to be viral related. In acute phases of infection, it is common to experience some smell loss as a result of nasal inflammation, mucosal edema, and obstruction of airflow into the olfactory cleft. In most cases, these episodes of smell loss are self-limiting and coincide with resolution of URI symptoms. However, in some cases the smell loss persists for months to years and this is presumed to occur through a more direct olfactory insult by the virus. It remains too early to know whether infection with SARS-CoV-2 causes persistent olfactory dysfunction. However, given the scale of this pandemic, if SARS-CoV-2 does cause chronic olfactory loss in even a small portion of those infected, then the overall population prevalence could be quite large. This review provides a brief, practical overview of viral-associated olfactory loss, realizing that evidence related to COVID-19 will likely not be clear for some time. Our goal is to highlight the existence and importance of this condition and provide information geared for both providers and patients. Practical suggestions regarding evaluation and treatment will be provided, realizing that there may be constraints on medical resources and the nature of this pandemic remains dynamic. This article is protected by copyright. All rights reserved.
DOI: 10.1002/alr.22578
PubMed: 32271490
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000262
- to stream PubMed, to step Curation: 000262
- to stream PubMed, to step Checkpoint: 000814
- to stream Ncbi, to step Merge: 003847
- to stream Ncbi, to step Curation: 003847
- to stream Ncbi, to step Checkpoint: 003847
- to stream Main, to step Merge: 000A26
- to stream Main, to step Curation: 000A26
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A primer on viral-associated olfactory loss in the era of COVID-19.</title>
<author><name sortKey="Soler, Zachary M" sort="Soler, Zachary M" uniqKey="Soler Z" first="Zachary M" last="Soler">Zachary M. Soler</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Otolaryngology - Head and Neck Surgery, Medical University of South Carolina, Charleston, SC.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Caroline du Sud</region>
</placeName>
<wicri:cityArea>Department of Otolaryngology - Head and Neck Surgery, Medical University of South Carolina, Charleston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Patel, Zara M" sort="Patel, Zara M" uniqKey="Patel Z" first="Zara M" last="Patel">Zara M. Patel</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Otolaryngology-Head and Neck Surgery, Stanford University, Palo Alto, CA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Department of Otolaryngology-Head and Neck Surgery, Stanford University, Palo Alto</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Turner, Justin H" sort="Turner, Justin H" uniqKey="Turner J" first="Justin H" last="Turner">Justin H. Turner</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University, Nashville, TN.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
<wicri:cityArea>Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University, Nashville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Holbrook, Eric H" sort="Holbrook, Eric H" uniqKey="Holbrook E" first="Eric H" last="Holbrook">Eric H. Holbrook</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Massachusetts Eye and Ear, Boston, MA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Massachusetts Eye and Ear, Boston</wicri:cityArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2020">2020</date>
<idno type="RBID">pubmed:32271490</idno>
<idno type="pmid">32271490</idno>
<idno type="doi">10.1002/alr.22578</idno>
<idno type="wicri:Area/PubMed/Corpus">000262</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000262</idno>
<idno type="wicri:Area/PubMed/Curation">000262</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000262</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000814</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000814</idno>
<idno type="wicri:Area/Ncbi/Merge">003847</idno>
<idno type="wicri:Area/Ncbi/Curation">003847</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">003847</idno>
<idno type="wicri:Area/Main/Merge">000A26</idno>
<idno type="wicri:Area/Main/Curation">000A26</idno>
<idno type="wicri:Area/Main/Exploration">000A26</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">A primer on viral-associated olfactory loss in the era of COVID-19.</title>
<author><name sortKey="Soler, Zachary M" sort="Soler, Zachary M" uniqKey="Soler Z" first="Zachary M" last="Soler">Zachary M. Soler</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Otolaryngology - Head and Neck Surgery, Medical University of South Carolina, Charleston, SC.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Caroline du Sud</region>
</placeName>
<wicri:cityArea>Department of Otolaryngology - Head and Neck Surgery, Medical University of South Carolina, Charleston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Patel, Zara M" sort="Patel, Zara M" uniqKey="Patel Z" first="Zara M" last="Patel">Zara M. Patel</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Otolaryngology-Head and Neck Surgery, Stanford University, Palo Alto, CA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Department of Otolaryngology-Head and Neck Surgery, Stanford University, Palo Alto</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Turner, Justin H" sort="Turner, Justin H" uniqKey="Turner J" first="Justin H" last="Turner">Justin H. Turner</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University, Nashville, TN.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
<wicri:cityArea>Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University, Nashville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Holbrook, Eric H" sort="Holbrook, Eric H" uniqKey="Holbrook E" first="Eric H" last="Holbrook">Eric H. Holbrook</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Massachusetts Eye and Ear, Boston, MA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Massachusetts Eye and Ear, Boston</wicri:cityArea>
</affiliation>
</author>
</analytic>
<series><title level="j">International forum of allergy & rhinology</title>
<idno type="eISSN">2042-6984</idno>
<imprint><date when="2020" type="published">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Early reports have suggested that smell loss may be an early symptom associated with the pandemic known as COVID-19. The possibility that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might cause olfactory dysfunction is certainly plausible. Patients presenting to specialized smell clinics are commonly diagnosed with upper respiratory infection (URI)-associated olfactory loss and most are presumed to be viral related. In acute phases of infection, it is common to experience some smell loss as a result of nasal inflammation, mucosal edema, and obstruction of airflow into the olfactory cleft. In most cases, these episodes of smell loss are self-limiting and coincide with resolution of URI symptoms. However, in some cases the smell loss persists for months to years and this is presumed to occur through a more direct olfactory insult by the virus. It remains too early to know whether infection with SARS-CoV-2 causes persistent olfactory dysfunction. However, given the scale of this pandemic, if SARS-CoV-2 does cause chronic olfactory loss in even a small portion of those infected, then the overall population prevalence could be quite large. This review provides a brief, practical overview of viral-associated olfactory loss, realizing that evidence related to COVID-19 will likely not be clear for some time. Our goal is to highlight the existence and importance of this condition and provide information geared for both providers and patients. Practical suggestions regarding evaluation and treatment will be provided, realizing that there may be constraints on medical resources and the nature of this pandemic remains dynamic. This article is protected by copyright. All rights reserved.</div>
</front>
</TEI>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Californie</li>
<li>Caroline du Sud</li>
<li>Massachusetts</li>
<li>Tennessee</li>
</region>
</list>
<tree><country name="États-Unis"><region name="Caroline du Sud"><name sortKey="Soler, Zachary M" sort="Soler, Zachary M" uniqKey="Soler Z" first="Zachary M" last="Soler">Zachary M. Soler</name>
</region>
<name sortKey="Holbrook, Eric H" sort="Holbrook, Eric H" uniqKey="Holbrook E" first="Eric H" last="Holbrook">Eric H. Holbrook</name>
<name sortKey="Patel, Zara M" sort="Patel, Zara M" uniqKey="Patel Z" first="Zara M" last="Patel">Zara M. Patel</name>
<name sortKey="Turner, Justin H" sort="Turner, Justin H" uniqKey="Turner J" first="Justin H" last="Turner">Justin H. Turner</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000A26 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000A26 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= SrasV1 |flux= Main |étape= Exploration |type= RBID |clé= pubmed:32271490 |texte= A primer on viral-associated olfactory loss in the era of COVID-19. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:32271490" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a SrasV1
This area was generated with Dilib version V0.6.33. |